Die molekulare Epidemiologie "Streptococcal Toxic Shock Syndrome" verursachender Gruppe-B-Streptokokken

Abstract

In the face of increasing numbers of toxic shock syndrome and/or necrotizing fasciitis caused by group B streptococci, multi locus sequence typing of 22 invasive and 30 colonizing isolates was conducted to determine whether a single clone/sequence type (ST) of S.agalactiae was causing those invasive infections. Although there were differences in the molecular epidemiology, no specific clone could be determined to be responsible for invasive infections. Among the 22 isolates that had caused streptococcal toxic shock syndrome, 7 were determined as ST-1.