Epidemiologische, ätiologische und kardiovaskuläre Charakterisierung von Patienten mit akutem cerebrovaskulären Ereignis - eine retrospektive Kohortenstudie von Patienten der Stroke Unit der Neurologischen Universitätsklinik Ulm

Abstract

Cerebrovascular events are a major cause of morbidity and mortality in Western countries. The presented retrospective study was made of the overall population, taken from Jan. 2001 to Dec. 2004, 284 patients for evaluation and characterized with regard to epidemiological and etiological conditions and their risk profile. Data collection took place within 6 hours of symptom appearance, the diagnosis by MRI. Epidemiological analysis showed a very representative patientgroup . There were no differences in number of risk factors between TIA and manifest ischemia. The number of riscfactors in both groups with ischemic events was significantly higher in ICBs. A special aspect of this work is the study of ECG changes that can be observed within the first 6 hours after stroke. How often pathological ECG findings occur in patients with established cerebrovascular events without evidence of heart disease. A high selected small cohort helps to assess whether should be described ECG changes either as an indication of latent heart disease or as a direct result of the cerebral event. Abnormal ECG changes occur at more than half of these patients. Repolarization occur at 17% without vs 21% with heart disease, it found a higher proportion of repolarization in patients with heart attacks compared to TIAs and ICBs. Prognosis (death after 90 days) shows no excess mortality in the group with healthy heart repolarization: the greatest number of deaths in the group of heart patients, and here is a dependency on advanced age and severity of neurological deficit.