Experimentelle Untersuchungen zu Genotoxizität von Insektiziden und Repellentien sowie den Kombinationen DEET-Pyridostigminbromid, DEET-Permethrin, Permethrin-Pyridostigminbromid und DEET-Pyridostigminbromid-Permethrin an humanen Lymphozyten

Abstract

The possible genotoxic effects of 17 insecticides and pesticides and four combinations were detected in human lymphocytes by the alkaline microgel electrophoresis assay ("comet assay"). We found a higher genotoxic effect by using the combinations DEET-Pyridostigminbromid, DEET-Permethrin, Permethrin-Pyridostigminbromid and DEET-Pyridostigminbromid-Permethrin. The combination DEET-Pyridostigminbromid-Permethrin first appeared at the gulf war. DEET was used as insect reppellent, Permethrin to the protection of the uniform against vectors and Pyridostigminbromid as a nerve agent prophylactic.