Der Einfluss von Tizanidin nach oraler Applikation auf die mittlere Reflexantwort der ischiocruralen Reflexantwort nach ventraler Tibiatranslation
Franke, Stephanie Katrin
LicenseStandard (Fassung vom 01.10.2008)
A rupture of the anterior cruciate ligament (ACL) is a common injury observed in the clinic. After an injury to the ACL the patients may notice a subjective instability. This instability has two components: mechanical instability and functional instability. Many authors have described a reflex arc between the ACL and the hamstrings, the Reflex Hamstring Contraction Latency (RHCL). Until now it is not known, how the components of the electromyograph response of the RHCL and the nerval components correspond. The aim of our study was to examine the components of the electromyographic response of the RHCL to understand the correlation of the components and the nerval afferents. Previous studies on the ankle joint used Tizanidine, an adrenozeptoragoniste, known for selective suppression of type II afferents. In 10 subjects we recorded EMG of the RHCL, applicated Tizanidine orally and repeated the examination. We could show a significant selective suppression of the integral of the medium contraction latency (after Tizanidine only 24,9 %). It seems likely that type II afferents build the MLR of the RHCL.
Subject HeadingsElektromyographie [GND]
Ligamentum cruciatum anterius [GND]
Anterior cruciate ligament [MeSH]
Clonidine. Analogs and derivatives [MeSH]