Methicillin-resistenter Staphylococcus aureus (MRSA) am Universitätsklinikum Ulm - eine retrospektive Analyse für den Zeitraum 2002 - 2006
Auch gedruckt in der BibliothekZ: J-H 13.238; W: W-H 11.682
Ressourcen- / MedientypDissertation, Text
Datum der Freischaltung2009-01-15
During the last years Methicillin-resistant S. aureus (MRSA) has become the most important nosocomial pathogen worldwide. Methods: Therefore the prevalence, microbiological findings and clinical outcome of MRSA-patients at Ulm University Hospital over a period of 4 years (2002 to 2006) has been analyzed. For this purpose all microbiological findings were checked and evaluated. 19 long-term-patients (patients with a colonisation with MRSA for at least 12 months) were identified. In the laboratory all available isolates of these long-term-patients were typed genotypically using pulsed field electrophoresis (PFGE). Results: 440 MRSA-patients were identified during the observation period. The typical MRSA-patient was male, 63 years old and was hospitalized in the surgical department. Only in 20 % of the cases three complete screenings were available after eradication therapy. 19 long-term-patients were identified. They had been colonized with MRSA between 12 and 49 months. Most of these patients developed a systemic infection caused by MRSA. All of these patients had at least one risk factor for long-term colonization with multiresistant pathogens. 13 patients carried one MRSA-strain, four patients had two strains and one patient was colonized by three different MRSA strains. Conclusions: With a MRSA prevalence of less than 10 % the situation at Ulm University Hospital is better than the average German MRSA-rates. The demographic and clinical characterics of the MRSA-patients in Ulm do not differ from the patient groups described in the literature. Screening for MRSA and compliance with control examinations could be improved. Education and information of HCWs and patients has a high priority to reach this goal. This investigation was one of the first works to demonstrate that MRSA-patients could be colonized by more than one MRSA-strain.
LizenzStandard (Fassung vom 01.10.2008)
Freie SchlagwörterMethicillin-resistenter Staphylococcus aureus