Stimulation der Frakturheilung an der Diaphyse der Schafstibia durch zyklische Distraktion und Kompression
Ehrnthaller, Christian Matthias
LizenzStandard (Fassung vom 01.10.2008)
Mechanical strain during callus distraction is known to stimulate osteogenesis. It is unclear whether this stimulus could be used to enhance the healing of a normal fracture without lengthening the bone. This study tested the hypothesis that a slow temporary distraction and compression of a diaphyseal osteotomy accelerate fracture healing. Fourteen sheep underwent a middiaphyseal osteotomy of the right tibia, stabilized by external fixation. An external fixator allowed either a temporary axial distraction (TD-group; n = 6) or a constant fixation (C-group; n = 8). Distraction began 7 days post-operatively at a rate of 0.5 mm twice per day for 2 days with subsequent shortening of 1.0 mm twice on the third day. The procedure was repeated 4 times. After 8 weeks the sheep were sacrificed and healing was evaluated using densitometric and biomechanical methods. Bending stiffness of the tibiae after 8 weeks was 58 % higher in the TD-group than in the C-group. The volume of the periosteal callus was significantly (p≤0.05) higher in the TD-group (3.9 cm3) than in the C-group (2.7 cm3). This study demonstrated the feasibility of fracture healing stimulation by the temporary application of distraction and compression.
Erstellung / Fertigstellung
Normierte SchlagwörterDistraktion [GND]
Ilizarov, Gavriil A. [GND]
Fracture healing [MeSH]