Stimulation der Frakturheilung an der Diaphyse der Schafstibia durch zyklische Distraktion und Kompression
Auch gedruckt in der BibliothekZ: J-H 13.129; W: W-H 11.576
Ehrnthaller, Christian Matthias
Ressourcen- / MedientypDissertation, Text
Datum der Freischaltung2008-12-21
Mechanical strain during callus distraction is known to stimulate osteogenesis. It is unclear whether this stimulus could be used to enhance the healing of a normal fracture without lengthening the bone. This study tested the hypothesis that a slow temporary distraction and compression of a diaphyseal osteotomy accelerate fracture healing. Fourteen sheep underwent a middiaphyseal osteotomy of the right tibia, stabilized by external fixation. An external fixator allowed either a temporary axial distraction (TD-group; n = 6) or a constant fixation (C-group; n = 8). Distraction began 7 days post-operatively at a rate of 0.5 mm twice per day for 2 days with subsequent shortening of 1.0 mm twice on the third day. The procedure was repeated 4 times. After 8 weeks the sheep were sacrificed and healing was evaluated using densitometric and biomechanical methods. Bending stiffness of the tibiae after 8 weeks was 58 % higher in the TD-group than in the C-group. The volume of the periosteal callus was significantly (p≤0.05) higher in the TD-group (3.9 cm3) than in the C-group (2.7 cm3). This study demonstrated the feasibility of fracture healing stimulation by the temporary application of distraction and compression.
LizenzStandard (Fassung vom 01.10.2008)
Ilizarov, Gavriil A.