Evaluierung von hochkonzentriertem jodhaltigem Kontrastmittel in der Multidetektor-Computer-Tomographie der Aorta mit automatischem Bolus-Tracking
Auch gedruckt in der BibliothekZ: J-H 11.961; W: W-H 11.445
Friedrich, Patricia Claude
Ressourcen- / MedientypDissertation, Text
Datum der Freischaltung2008-07-22
Purpose: To objectively evaluate the benefit of a contrast medium with high concentration Iodine for Multi-Detector CT Angiography (MDCTA) of the aorta using automatic bolus tracking. - Materials and methods: A total of 100 consecutive MDCTA examinations of the entire aorta were evaluated. All scans were performed on a 40 channel MDCT scanner. A contrast medium with a high Iodine concentration of 400 mg/ml (Imeron 400, Bracco, Milano, Italy) was administered by power injector at a dose of 1.2 ml/kg BW and at a rate of 3.5 ml/sec, followed by a saline chaser. Scanning was initiated by automated bolus tracking with a delay of 6 sec after attaining a measured threshold of 150 HU in the descending aorta. Time-density distributions calculated from the ascending aorta downstream to the common femoral arteries were graded as from poor to excellent based on contrast density, homogeneity, and timing of the scan acquisition. - Results: Evaluated aortic lesions included 23 thoracic and 39 abdominal aneurysms and 30 aortic dissections. The mean (± SD) overall arterial density of MDCTA was 306 ± 66 HU (range: 129 - 476 HU). Averaged arterial contrast density was rated good or better in 92 cases (> 200 HU) while contrast homogeneity was rated good or better in 83 cases. Automatic bolus tracking permitted accurate scanning during peak contrast enhancement in 87 cases. The 13 mistimed examinations comprised 12 MDCTA studies that were started early and one that was started late. In all early scans the contrast density was still considered good or better. - Conclusion: The combination of high concentration contrast medium and automatic bolus tracking allows reliable MDCTA of the entire aorta including the pelvic axis with excellent and homogeneous contrast distribution in a variety of aortic pathologies.
LizenzStandard (Fassung vom 03.05.2003)