Notwendigkeit einer Druckveränderung bei Patienten mit CPAP (Continuous Positive Airway Pressure)-Therapie 2 - 3 Monate nach der Ersteinstellung
LicenseStandard (Fassung vom 03.05.2003)
Study objectives: To investigate the need for pressure change in a larger group of patients with sleep disordered breathing (SDB) several weeks after initial CPAP (continuous positive airway pressure)/Bilevel-CPAP and auto-CPAP titration. Design: Prospective cohort study of consecutive patients with sleep disordered breathing and CPAP/Bilevel-CPAP/auto-CPAP therapy. Setting: Sleep laboratory in a regional hospital. Patients: 905 patients (740 m, 165 f) with SDB confirmed by polysomnography (PSG) and therapeutic intervention with CPAP/Bilevel-CPAP. Measurements and interventions: After baseline PSG, patients underwent in laboratory PSG for titration of CPAP, Bilevel-CPAP or auto-CPAP. Several weeks (mean 11) after CPAP initiation in a single night PSG patients were restudied and the differences in CPAP pressure between initial treatment night and re-titration night recorded. Anthropometric data, PSG data and Epworth Sleepiness scale and Berlin Questionnnaire scores were correlated to changes in CPAP pressure of first and control titration. Results: Pressure change was needed in the majority of patients (58,2 %, n 511). Pressure increase was more frequent than pressure recuction [411 (46,8 %) vs. 100 (11,4 %)]. Mean pressure increase in CPAP was 1,3 mbar, mean decrease 1,6 mbar, in Bilevel-CPAP mean increase in inspiratory pressure was 1,3 mbar, in exspiratory pressure 0,8 mbar, decrease in inspiratory pressure 1,9 mbar and 1,4 mbar in exspiratory pressure. No correlation was found between anthropometric data of patients, sleep efficacy or questionnaire scores and pressure change. Conclusion: Pressure changes are necessary in the majority of patients several weeks after CPAP initiation. Therefore re-evaluation of CPAP patients in a certain time frame after CPAP is useful.
Subject HeadingsCPAP [GND]
Continuous positive airway pressure [MeSH]
Sleep apnea syndromes [MeSH]