Stepwise acquirement of hallmark neuropathology in FUS-ALS iPSC models depends on mutation type and neuronal aging

Erstveröffentlichung
2015Authors
Japtok, Julia
Lojewski, Xenia
Naumann, Marcel
Klingenstein, Moritz
Reinhardt, Peter
Wissenschaftlicher Artikel
Published in
Neurobiology of Disease ; 82 (2015). - S. 420-429. - ISSN 0969-9961. - eISSN 1095-953X
Link to publication
https://dx.doi.org/10.1016/j.nbd.2015.07.017Faculties
Medizinische FakultätInstitutions
Institut für Anatomie und ZellbiologieUKU. Klinik für Neurologie
Subject headings
[Free subject headings]: Amyotrophic lateral sclerosis | Frontotemporal dementia | Fused in sarcoma | Translated in sarcoma | RNA granules | Stress granules | Aggregate prone disease | Disease spreading | Cortical neurodegeneration | Motor neuron disease | FUS-FTLD | iPSC | Human cell models | amyotrophic-lateral-sclerosis | frontotemporal lobar degeneration | nuclear-localization signal | pluripotent stem-cells | wild-type fus | sarcoma fus | mutant fus | fet proteins | rna[DDC subject group]: DDC 610 / Medicine & health