Neonatal Fc receptor FcRn is involved in intracellular transport of the Fc fusion protein aflibercept and its transition through retinal endothelial cells

Erstveröffentlichung
2017Authors
Deissler, Heidrun L.
Lang, Gerhard K.
Lang, Gabrielle E.
Wissenschaftlicher Artikel
Published in
Experimental Eye Research ; 154 (2017). - S. 39-46. - ISSN 0014-4835. - eISSN 1096-0007
Link to publication
https://dx.doi.org/10.1016/j.exer.2016.11.007Institutions
UKU. Klinik für AugenheilkundeSubject headings
[Free subject headings]: Retinal endothelial cells | Aflibercept Fc fusion protein | IgG | Neonatal Fc receptor | Internalization | Transport | Transcytosis | diabetic macular edema | therapeutic antibodies | intravitreal injection | crystal-structure | vegf-trap | human-igg | ranibizumab | bevacizumab | eye | fragment[DDC subject group]: DDC 610 / Medicine & health