Increased susceptibility of CD4+T cells from elderly individuals to HIV-1 infection and apoptosis is associated with reduced CD4 and enhanced CXCR4 and FAS surface expression levels

Erstveröffentlichung
2015Autoren
Heigele, Anke
Joas, Simone
Regensburger, Kerstin
Kirchhoff, Frank
Wissenschaftlicher Artikel
Erschienen in
Retrovirology ; 12 (2015). - Art.-Nr. 86. - ISSN 1742-4690
Link zur Veröffentlichung
https://dx.doi.org/10.1186/s12977-015-0213-1Institutionen
UKU. Institut für Molekulare VirologieProjekt uulm
IGradU / International Graduate School der Universität Ulm
Schlagwörter
[Freie Schlagwörter]: HIV | Aging | T cell subsets | CXCR4 | FAS | Apoptosis | immunodeficiency-virus type-1 | human peripheral-blood | t-cells | disease progression | in-vivo | replicative senescence | immune activation | gene-expression | older-adults | viral load[DDC Sachgruppe]: DDC 610 / Medicine & health