IFI16 is required for DNA sensing in human macrophages by promoting production and function of cGAMP

Erstveröffentlichung
2017Authors
Jonsson, K. L.
Laustsen, A.
Krapp, C.
Skipper, K. A.
Thavachelvam, K.
Wissenschaftlicher Artikel
Published in
Nature Communications ; 8 (2017). - Art.-Nr. 14391. - ISSN 2041-1723
Link to publication
https://dx.doi.org/10.1038/ncomms14391Institutions
UKU. Institut für Molekulare VirologieEU Project uulm
HIT HIDDEN HIV / Paving the way towards HIV eradication/control / EC / FP7 / 305762
Project uulm
IGradU / International Graduate School der Universität Ulm
Subject headings
[Free subject headings]: gmp-amp synthase | innate immune sensor | interferon response | intracellular dna | cyclic dinucleotide | aim2-like receptors | nucleic-acids | sting pathway | rna viruses | a virus[DDC subject group]: DDC 610 / Medicine & health