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AutorWohlfart, Petradc.contributor.author
Aufnahmedatum2016-03-14T13:41:19Zdc.date.accessioned
In OPARU verfügbar seit2016-03-14T13:41:19Zdc.date.available
Jahr der Erstellung2006dc.date.created
ZusammenfassungPurpose: The purpose of this retrospective, blinded study was to evaluate the additional value of [18F]FDG PET/CT in comparison with PET alone with malignant melanoma (MM). Methods: A total of 127 consecutive studies of patients with known MM referred for a whole-body PET/CT examination were included in this study. PET aloneand integrated PET/CT study were independently and separately interpreted without awareness of the clinical information. One score each was applied for certainty of lesion localisation and for certainty of lesion haracterisation. Verification of the findings was subsequently performed using all available clinical, pathological (n=30) and follow-up information. Results: The number of lesions with an uncertain localisation was significantly (p<0.001) reduced by PET/CT in comparison with PET alone. In line with this increase in certainty integrated PET/CT reading also improved certainty in characterisation of lesions, however, this did not reach significance (p=0.057) compared versus PET alone. Respectively, PET and PET/CT showed a sensitivity of 88% and 91%, a specificity of 91 and 94%, a positive predictive value of 94% and 96% and a negative predictive value of 82% and 87%. Conclusion: Integrated PET/CT offers a significant benefit in lesion localisation and an improvement in lesion characterisation compared with PET alone. The benefit is not as great as that reported for other tumour entities, which may be due to the high avidity of MM for [18F]FDG.dc.description.abstract
Sprachededc.language.iso
Verbreitende StelleUniversität Ulmdc.publisher
LizenzStandard (Fassung vom 03.05.2003)dc.rights
Link zum Lizenztexthttps://oparu.uni-ulm.de/xmlui/license_v1dc.rights.uri
Schlagwort[18F]FDG PETdc.subject
DDC-SachgruppeDDC 610 / Medicine & healthdc.subject.ddc
MeSHMelanomadc.subject.mesh
MeSHOncologydc.subject.mesh
TitelPET/CT zum Staging und Restaging bei Patienten mit malignem Melanomdc.title
RessourcentypDissertationdc.type
DOIhttp://dx.doi.org/10.18725/OPARU-819dc.identifier.doi
URNhttp://nbn-resolving.de/urn:nbn:de:bsz:289-vts-59148dc.identifier.urn
GNDPositronen-Emissions-Tomografiedc.subject.gnd
FakultätMedizinische Fakultätuulm.affiliationGeneral
Datum der Freischaltung2007-05-29T17:46:58Zuulm.freischaltungVTS
Peer-Reviewneinuulm.peerReview
Signatur DruckexemplarZ: J-H 11.474 ; W: W-H 9.592uulm.shelfmark
DCMI MedientypTextuulm.typeDCMI
VTS-ID5914uulm.vtsID
KategoriePublikationenuulm.category


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