Newly identified c-KIT receptor tyrosine kinase ITD in childhood AML induces ligand-independent growth and is responsive to a synergistic effect of imatinib and rapamycin

Erstveröffentlichung
2006Authors
Corbacioglu, Salim
Kilic, Mehtap
Westhoff, Mike-Andrew
Reinhardt, Dirk
Fulda, Simone
Wissenschaftlicher Artikel
Published in
Blood ; 108 (2006), 10. - S. 3504-3513. - ISSN 0006-4971
Link to publication
https://dx.doi.org/10.1182/blood-2006-05-021691Institutions
UKU. Klinik für Kinder- und JugendmedizinSubject headings
[Free subject headings]: acute myeloid-leukemia | gastrointestinal stromal tumors | internal tandem duplication | stem-cell factor | signal-transduction | juxtamembrane domain | cancer cells | phosphatidylinositol 3-kinase | activating mutations | hematopoietic-cells[DDC subject group]: DDC 610 / Medicine & health