Small molecule XIAP inhibitors cooperate with TRAIL to induce apoptosis in childhood acute leukemia cells and overcome Bcl-2-mediated resistance

Fakler, Melanie; Loeder, Sandra; Vogler, Meike; Schneider, Katja; Jeremias, Irmela; Debatin, Klaus-Michael; Fulda, Simone

Erstveröffentlichung

2009

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Wissenschaftlicher Artikel

Authors

Fakler, Melanie

Loeder, Sandra

Vogler, Meike

Schneider, Katja

Jeremias, Irmela

et al.

Institutions

UKU. Klinik für Kinder- und Jugendmedizin

Published in

Blood ; 113 (2009), 8. - S. 1710-1722. - ISSN 0006-4971

Link to publication

https://dx.doi.org/10.1182/blood-2007-09-114314

Funding information

Deutsche Forschungsgemeinschaft (Bonn, Germany)
Deutsche Krebshilfe (Bonn, Germany)
Kind-Philipp Stiftung (Bonn, Germany)
EU (Apoptrain APO-SYS, Brussels, Belgium) [IAP6/18]

Keywords

acute lymphoblastic-leukemia; pancreatic-carcinoma cells; acute myeloid-leukemia; signaling complex; t-cells; monoclonal-antibody; antitumor-activity; tumor-cells; in-vivo; death

Dewey Decimal Group

DDC 610 / Medicine & health

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