TRAIL-Induced Apoptosis Is Preferentially Mediated via TRAIL Receptor 1 in Pancreatic Carcinoma Cells and Profoundly Enhanced by XIAP Inhibitors

Erstveröffentlichung
2010
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Wissenschaftlicher Artikel


Authors
Stadel, Dominic
Mohr, Andrea
Ref, Caroline
MacFarlane, Marion
Zhou, Shaoxia
et al.
Institutions
UKU. Klinik für Kinder- und Jugendmedizin
Institut für Klinische Chemie
UKU. Institut für Pathologie
Published in
Clinical Cancer Research ; 16 (2010), 23. - S. 5734-5749. - ISSN 1078-0432
Link to publication
https://dx.doi.org/10.1158/1078-0432.CCR-10-0985
Funding information
Deutsche Forschungsgemeinschaft (DFG)
Deutsche Krebshilfe
European Community
[IAP6/18]
Keywords
agonistic monoclonal-antibody; growth in-vivo; selective mutants; cancer-therapy; mapatumumab; targets; death; pathways; vitro; ligand-receptor-2
Dewey Decimal Group
DDC 610 / Medicine & health
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