Targeting XIAP bypasses Bcl-2-mediated resistance to TRAIL and cooperates with TRAIL to suppress pancreatic cancer growth in vitro and in vivo

Erstveröffentlichung
2008
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Wissenschaftlicher Artikel


Authors
Vogler, Meike
Walczak, Henning
Stadel, Dominic
Haas, Tobias L.
Genze, Felicitas
et al.
Institutions
UKU. Klinik für Kinder- und Jugendmedizin
UKU. Klinik für Urologie und Kinderurologie
UKU. Institut für Naturheilkunde und Klinische Pharmakologie
Published in
Cancer Research ; 68 (2008), 19. - S. 7956-7965. - ISSN 0008-5472
Link to publication
https://dx.doi.org/10.1158/0008-5472.CAN-08-1296
Funding information
Deutsche Forschungsgemeinschaft (DFG)
Deutsche Krebshilfe
IAP6/18
European Community
Keywords
human prostate-cancer; cytochrome-c release; induced apoptosis; cell-death; carcinoma cells; decoy receptors; inhibition; pathways; proteins; drug
Dewey Decimal Group
DDC 610 / Medicine & health
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