Impairment of lysosomal integrity by B10, a glycosylated derivative of betulinic acid, leads to lysosomal cell death and converts autophagy into a detrimental process

Erstveröffentlichung
2012Authors
Gonzalez, P.
Mader, I.
Tchoghandjian, A.
Enzenmüller, Stefanie
Cristofanon, S.
Wissenschaftlicher Artikel
Published in
Cell Death and Differentiation ; 19 (2012), 8. - S. 1337-1346. - ISSN 1350-9047
Link to publication
https://dx.doi.org/10.1038/cdd.2012.10Institutions
UKU. Klinik für Kinder- und JugendmedizinSubject headings
[Free subject headings]: betulinic acid | apoptosis | autophagy | lysosomes | induced apoptosis | glioma-cells | inhibition | caspases | cancer | macroautophagy | sensitivity | activation | expression | proteases[DDC subject group]: DDC 610 / Medicine & health