Pre-BCR signaling in precursor B-cell acute lymphoblastic leukemia regulates PI3K/AKT, FOXO1 and MYC, and can be targeted by SYK inhibition
Erstveröffentlichung
2016
Wissenschaftlicher Artikel
Published in
Leukemia ; 30 (2016), 6. - S. 1246-1254. - ISSN 0887-6924. - eISSN 1476-5551
Link to publication
https://dx.doi.org/10.1038/leu.2016.9Institutions
UKU. Klinik für Kinder- und JugendmedizinUKU. Institut für Immunologie
DFG Project THU
SFB 1074 / Experimentelle Modelle und klinische Translation bei Leukämien / DFG / 217328187
Subject headings
[Free subject headings]: chronic lymphocytic-leukemia | tyrosine kinase syk | gene-expression | receptor checkpoint | negative selection | tumor-suppressor | cycle arrest | chain gene | differentiation | lymphoma[DDC subject group]: DDC 610 / Medicine & health