Antioxidative therapy in an ex vivo human cartilage trauma-model: attenuation of trauma-induced cell loss and ECM-destructive enzymes by N-acetyl cysteine

Erstveröffentlichung
2016
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Wissenschaftlicher Artikel


Authors
Riegger, J.
Joos, H.
Palm, Hans-Georg
Friemert, Benedikt
Reichel, H.
et al.
Institutions
UKU. Klinik für Orthopädie
Bundeswehrkrankenhaus Ulm (BWK)
UKU. Institut für Unfallchirurgische Forschung und Biomechanik
Published in
Osteoarthritis and Cartilage ; 24 (2016), 12. - S. 2171-2180. - ISSN 1063-4584. - eISSN 1522-9653
Link to publication
https://dx.doi.org/10.1016/j.joca.2016.07.019
Funding information
German Department of Defence (Civil-Military Network for Regenerative Medicine, Ulm, Germany) [GZE/U2AD/CD524/DF560]
Keywords
Posttraumatic osteoarthritis; N-acetyl cysteine; ECM degradation; Chondroprotection; Cell protection; Mechanical loading; necrosis-factor-alpha; articular-cartilage; osteoarthritic cartilage; gene-expression; hydrogen-peroxide; induced apoptosis; epithelial-cells; nitric-oxide; tnf-alpha; c-fos
Dewey Decimal Group
DDC 610 / Medicine & health
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