Antioxidative therapy in an ex vivo human cartilage trauma-model: attenuation of trauma-induced cell loss and ECM-destructive enzymes by N-acetyl cysteine

Riegger, J.; Joos, H.; Palm, H. G.; Friemert, B.; Reichel, H.; Ignatius, Anita; Brenner, R. E.

Erstveröffentlichung

2016

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Wissenschaftlicher Artikel

Authors

Riegger, J.

Joos, H.

Palm, H. G.

Friemert, B.

Reichel, H.

et al.

Institutions

UKU. Klinik für Orthopädie
Bundeswehrkrankenhaus Ulm (BWK)
UKU. Institut für Unfallchirurgische Forschung und Biomechanik

Published in

Osteoarthritis and Cartilage ; 24 (2016), 12. - S. 2171-2180. - ISSN 1063-4584. - eISSN 1522-9653

Link to publication

https://dx.doi.org/10.1016/j.joca.2016.07.019

Funding information

German Department of Defence (Civil-Military Network for Regenerative Medicine, Ulm, Germany) [GZE/U2AD/CD524/DF560]

Keywords

Posttraumatic osteoarthritis; N-acetyl cysteine; ECM degradation; Chondroprotection; Cell protection; Mechanical loading; necrosis-factor-alpha; articular-cartilage; osteoarthritic cartilage; gene-expression; hydrogen-peroxide; induced apoptosis; epithelial-cells; nitric-oxide; tnf-alpha; c-fos

Dewey Decimal Group

DDC 610 / Medicine & health

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