Midostaurin plus Chemotherapy for Acute Myeloid Leukemia with a FLT3 Mutation

Stone, Richard M.; Mandrekar, Sumithra J.; Sanford, Ben L.; Laumann, Kristina; Geyer, Susan; Bloomfield, Clara D.; Thiede, Christian; Prior, Thomas W.; Döhner, Konstanze; Marcucci, Guido; Lo-Coco, Francesco; Klisovic, Rebecca B.; Wei, Andrew; Sierra, Jorge; Sanz, Miguel A.; Brandwein, Joseph M.; de Witte, Theo; Niederwieser, Dietger; Appelbaum, Frederick R.; Medeiros, Bruno C.; Tallman, Martin S.; Krauter, Jürgen; Schlenk, Richard F.; Ganser, Arnold; Serve, Hubert; Ehninger, Gerhard; Amadori, Sergio; Larson, Richard A.; Döhner, Hartmut

Erstveröffentlichung

2017

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Wissenschaftlicher Artikel

Authors

Stone, Richard M.

Mandrekar, Sumithra J.

Sanford, Ben L.

Laumann, Kristina

Geyer, Susan

et al.

Institutions

UKU. Klinik für Innere Medizin III

Published in

New England Journal of Medicine ; 377 (2017), 5. - S. 454-464. - ISSN 0028-4793. - eISSN 1533-4406

Link to publication

https://dx.doi.org/10.1056/NEJMoa1614359

Funding information

National Cancer Institute
Novartis

Keywords

internal tandem duplication; acute myelogenous leukemia; tyrosine kinase inhibitor; stem-cell transplantation; phase-i; favorable prognosis; poor-prognosis; wild-type; pkc412; trial

Dewey Decimal Group

DDC 610 / Medicine & health

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