Loss of cooperativity of secreted CD40L and increased dose-response to IL4 on CLL cell viability correlates with enhanced activation of NF-kB and STAT6

Bhattacharya, Nupur; Reichenzeller, Michaela; Caudron-Herger, Maiwen; Haebe, Sarah; Brady, Nathan; Diener, Susanne; Nothing, Maria; Döhner, Hartmut; Stilgenbauer, Stephan; Rippe, Karsten; Mertens, Daniel

Erstveröffentlichung

2015

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Wissenschaftlicher Artikel

Autoren

Bhattacharya, Nupur

Reichenzeller, Michaela

Caudron-Herger, Maiwen

Haebe, Sarah

Brady, Nathan

et al.

Institutionen

UKU. Klinik für Innere Medizin III

Erschienen in

International Journal of Cancer ; 136 (2015), 1. - S. 65-73. - ISSN 0020-7136. - eISSN 1097-0215

Link zur Veröffentlichung

https://dx.doi.org/10.1002/ijc.28974

Förderinformationen

Deutsche Krebshilfe [109539]
Helmholtz Virtual Institute [VH-VI-404]
CancerEpiSys project in the BMBF CancerSys program [0316049C, 0316049A]

Schlagwörter

sCD40L; IL4; chronic lymphocytic leukemia; apoptosis; NF-kB; chronic lymphocytic-leukemia; normal b-cells; kappa-b; in-vitro; spontaneous apoptosis; signaling mechanisms; survival; ligand; proliferation; receptor

DDC-Sachgruppe

DDC 610 / Medicine & health

Metadata

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