Nilotinib hampers the proliferation and function of CD8(+) T lymphocytes through inhibition of T cell receptor signalling

Chen, J.; Schmitt, A.; Chen, B.; Rojewski, M.; Ruesseler, V.; Fei, F.; Yu, Y.; Yu, X.; Ringhoffer, M.; von Harsdorf, S.; Greiner, J.; Goetzz, M.; Guillaume, P.; Döhner, Hartmut; Bunjes, D.; Schmitt, M.

Erstveröffentlichung

2008

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Wissenschaftlicher Artikel

Authors

Chen, J.

Schmitt, A.

Chen, B.

Rojewski, M.

Ruesseler, V.

et al.

Institutions

UKU. Klinik für Innere Medizin III
Institut für Klinische Transfusionsmedizin und Immungenetik Ulm gGmbH (IKT)

Published in

Journal of Cellular and Molecular Medicine ; 12 (2008), 5B. - S. 2107-2118. - ISSN 1582-1838

Link to publication

https://dx.doi.org/10.1111/j.1582-4934.2008.00234.x

Keywords

nilotinib; lymphocyte proliferation; functional activation; healthy donor; chronic myeloid leukaemia; chronic myeloid-leukemia; chronic myelogenous leukemia; in-situ hybridization; bcr-abl; imatinib mesylate; kinase-inhibitor; aminopyrimidine inhibitor; philadelphia-chromosome; tyrosine kinase; dendritic cells

Dewey Decimal Group

DDC 610 / Medicine & health

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