CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPAR gamma signaling

Faber, Katrin; Bullinger, Lars; Ragu, Christine; Garding, Angela; Mertens, Daniel; Miller, Christina; Martin, Daniela; Walcher, Daniel; Doehner, Konstanze; Döhner, Hartmut; Claus, Rainer; Plass, Christoph; Sykes, Stephen M.; Lane, Steven W.; Scholl, Claudia; Froehling, Stefan

Erstveröffentlichung

2013

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Wissenschaftlicher Artikel

Authors

Faber, Katrin

Bullinger, Lars

Ragu, Christine

Garding, Angela

Mertens, Daniel

et al.

Institutions

UKU. Klinik für Innere Medizin III
UKU. Klinik für Innere Medizin II

Published in

Journal of Clinical Investigation ; 123 (2013), 1. - S. 299-314. - ISSN 0021-9738

Link to publication

https://dx.doi.org/10.1172/JCI64745

Funding information

Deutsche Jose Carreras Leukamie-Stiftung [DJCLS R 09/12]
German Research Foundation
Leukaemia Foundation of Australia
Emmy Noether Fellowship from the German Research Foundation
European Hematology Association-Jose Carreras Foundation Young Investigator Fellowship

Keywords

acute myeloid-leukemia; activated receptor-gamma; homeobox gene cdx2; cancer cell-lines; tumor-suppressor; colon-cancer; intestinal metaplasia; transcription factors; colorectal-cancer; ectopic expression

Dewey Decimal Group

DDC 610 / Medicine & health

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