CDX2-driven leukemogenesis involves KLF4 repression and deregulated PPAR gamma signaling

Faber, Katrin; Bullinger, Lars; Ragu, Christine; Garding, Angela; Mertens, Daniel; Miller, Christina; Martin, Daniela; Walcher, Daniel; Doehner, Konstanze; Döhner, Hartmut; Claus, Rainer; Plass, Christoph; Sykes, Stephen M.; Lane, Steven W.; Scholl, Claudia; Froehling, Stefan

Erstveröffentlichung

2013

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Wissenschaftlicher Artikel

Autoren

Faber, Katrin

Bullinger, Lars

Ragu, Christine

Garding, Angela

Mertens, Daniel

et al.

Institutionen

UKU. Klinik für Innere Medizin III
UKU. Klinik für Innere Medizin II

Erschienen in

Journal of Clinical Investigation ; 123 (2013), 1. - S. 299-314. - ISSN 0021-9738

Link zur Veröffentlichung

https://dx.doi.org/10.1172/JCI64745

Förderinformationen

Deutsche Jose Carreras Leukamie-Stiftung [DJCLS R 09/12]
German Research Foundation
Leukaemia Foundation of Australia
Emmy Noether Fellowship from the German Research Foundation
European Hematology Association-Jose Carreras Foundation Young Investigator Fellowship

Schlagwörter

acute myeloid-leukemia; activated receptor-gamma; homeobox gene cdx2; cancer cell-lines; tumor-suppressor; colon-cancer; intestinal metaplasia; transcription factors; colorectal-cancer; ectopic expression

DDC-Sachgruppe

DDC 610 / Medicine & health

Metadata

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