Complex karyotypes and KRAS and POT1 mutations impact outcome in CLL after chlorambucil-based chemotherapy or chemoimmunotherapy

Herling, Carmen Diana; Klaumuenzer, Marion; Rocha, Cristiano Krings; Altmueller, Janine; Thiele, Holger; Bahlo, Jasmin; Kluth, Sandra; Crispatzu, Giuliano; Herling, Marco; Schiller, Joanna; Engelke, Anja; Tausch, Eugen; Döhner, Hartmut; Fischer, Kirsten; Goede, Valentin; Nuernberg, Peter; Reinhardt, Hans Christian; Stilgenbauer, Stephan; Hallek, Michael; Kreuzer, Karl-Anton

Erstveröffentlichung

2016

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Wissenschaftlicher Artikel

Authors

Herling, Carmen Diana

Klaumuenzer, Marion

Rocha, Cristiano Krings

Altmueller, Janine

Thiele, Holger

et al.

Institutions

UKU. Klinik für Innere Medizin III

Published in

Blood ; 128 (2016), 3. - S. 395-404. - ISSN 0006-4971. - eISSN 1528-0020

Link to publication

https://dx.doi.org/10.1182/blood-2016-01-691550

Funding information

VolkswagenStiftung (Lichtenberg Program)
Deutsche Forschungsgemeinschaft (DFG) [KFO-286]
Deutsche José Carreras Leukämie-Stiftung e.V., Germany [R12/26, R13/33]
Helmholtz-Gemeinschaft (Preclinical Comprehensive Cancer Center)
Else Kroner-Fresenius Stiftung grant [EKFS-2014-A06]
etc.

Keywords

chronic lymphocytic-leukemia; identifies recurrent mutations; chromosomal translocations; genetic-characterization; metaphase cytogenetics; independent predictor; genomic aberrations; telomere length; splicing factor; poor-prognosis

Dewey Decimal Group

DDC 610 / Medicine & health

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