Trajectory and determinants of agreement between parental and physicians' reports of childhood atopic dermatitis
peer-reviewed
Erstveröffentlichung
2022-09-21Authors
Peng, Zhuoxin
Braig, Stefanie
Kurz, Deborah
Weiss, Johannes M.
Weidinger, Stephan
Wissenschaftlicher Artikel
Published in
Pediatric Allergy and Immunology ; 33 (2022), 9. - ISSN 0905-6157. - eISSN 1399-3038
Link to original publication
https://dx.doi.org/10.1111/pai.13855Faculties
Medizinische FakultätInstitutions
Institut für Epidemiologie und Medizinische BiometrieUKU. Klinik für Dermatologie und Allergologie
Document version
published version (publisher's PDF)Abstract
Abstract
Background
Parent self‐administered reports are commonly used in studies on childhood atopic dermatitis (AD) but data on its validity are sparse. We aimed to examine the agreement between parent‐ and physician‐reported measures of childhood AD throughout early life and identify the determinants.
Methods
In this prospective cohort study, we used data of 449 infants and their mothers recruited in the Ulm SPATZ Health Study in Germany. Longitudinal data of parental and children's caring physicians' reports were used to assess the point and cumulative agreement of parent‐ and physician‐reported AD diagnoses, AD onset age, and trend of agreement at child ages between 1 and 6 years overall and by child and parent demographics and health conditions. A Generalized Estimating Equation model was fitted to identify factors associated with the sensitivity of parent reports.
Results
The point agreement between parent‐ and physician‐reported AD was substantial at the age of 1 (kappa = 0.63, 95% CI: 0.51–0.75) but declined with age and became fair after the age of 3 (kappa < 0.40). The cumulative agreement remained moderate at the age of 6 (kappa = 0.51, 95% CI: 0.43–0.60). Parents had a bias towards delayed reporting of the AD onset age. The AD severity was the only strong determinant for the agreement of AD diagnoses and largely explained the variance of the sensitivity of parent reports.
Conclusion
The disagreement between parent‐ and physician‐reported AD increases with child age, likely due to the change of AD severity. Using parent‐reported data might miss a substantial portion of mild childhood AD cases.
Project uulm
SPATZ / Ulmer SPATZ Gesundheitsstudie / Medizinische Fakultät der Universität Ulm
Is supplemented by
https://onlinelibrary.wiley.com/action/downloadSupplement?doi=10.1111%2Fpai.13855&file=pai13855-sup-0001-supinfo.docxSubject headings
[GND]: Kind | Endogenes Ekzem | Atopie | Kohortenanalyse[MeSH]: Child | Dermatitis, Atopic | Cohort studies
[Free subject headings]: parental report | physician report | recall bias | severity
[DDC subject group]: DDC 610 / Medicine & health
Metadata
Show full item recordDOI & citation
Please use this identifier to cite or link to this item: http://dx.doi.org/10.18725/OPARU-48918
Peng, Zhuoxin et al. (2023): Trajectory and determinants of agreement between parental and physicians' reports of childhood atopic dermatitis. Open Access Repositorium der Universität Ulm und Technischen Hochschule Ulm. http://dx.doi.org/10.18725/OPARU-48918
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