Pharmacokinetics of codeine and its metabolite morphine in ultra-rapid metabolizers due to CYP2D6 duplication

Erstveröffentlichung
2007Authors
Kirchheiner, J.
Schmidt, H.
Tzvetkov, Mladen Vassilev
Keulen, J-Tha
Lötsch, Jorn
Wissenschaftlicher Artikel
Published in
Pharmacogenomics Journal ; 7 (2007), 4. - S. 257-265. - ISSN 1470-269X. - eISSN 1473-1150
Link to publication
https://dx.doi.org/10.1038/sj.tpj.6500406Institutions
UKU. Institut für Naturheilkunde und Klinische PharmakologieSubject headings
[Free subject headings]: CYP2D6 | ultrarapid metabolism | gene duplication | codeine | MU-OPIOID RECEPTOR | EXTENSIVE METABOLIZERS | CYTOCHROME-P450 2D6 | ADVERSE EVENTS | GENE | DEBRISOQUINE | POOR | POLYMORPHISM | GENOTYPE | IMPACT[DDC subject group]: DDC 570 / Life sciences | DDC 610 / Medicine & health