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AuthorStrohäker, Jensdc.contributor.author
AuthorWiegand, Lisadc.contributor.author
AuthorBeltzer, Christiandc.contributor.author
AuthorKönigsrainer, Alfreddc.contributor.author
AuthorLadurner, Ruthdc.contributor.author
AuthorMeier, Ankedc.contributor.author
Date of accession2022-06-27T12:20:51Zdc.date.accessioned
Available in OPARU since2022-06-27T12:20:51Zdc.date.available
Date of first publication2021-01-13dc.date.issued
Abstract(1) Background: Cholecystitis and cholangitis are among the most common diseases treated by general surgery. Gallstones lead to inflammation and bacterial infection of the biliary tract. Biliary infections can lead to live threatening bacteremia and liver abscesses. The true role of anaerobes remains unclear. (2) Methods: We retrospectively analyzed bacterial cultures from biliary samples obtained from bile ducts and gallbladders at our tertiary care center. Patient characteristics and clinical outcomes were analyzed. (3) Results: In our database of 1719 patients, 365 patients had microbial testing, of which 42 grew anaerobic bacteria. Anaerobes were more frequently cultured in patients with hepatic abscesses and gallbladder perforation. These patients were older and had more comorbidities than the control group. The overall outcomes of all patients were favorable and the resistance rate to commonly used antibiotics remained low. (4) Conclusions: Anaerobes in biliary tract infections appear to be underdiagnosed and more prevalent in the elderly with advanced disease. Due to low antibiotic resistance, the combination of source control and adjunct anti-infective treatment leads to favorable outcomes.dc.description.abstract
Languageendc.language.iso
PublisherUniversität Ulmdc.publisher
LicenseCC BY 4.0 Internationaldc.rights
Link to license texthttps://creativecommons.org/licenses/by/4.0/dc.rights.uri
Keywordanaerobic infectiondc.subject
Keywordcholecystitisdc.subject
Keywordcholangitisdc.subject
Keywordbiliary tract infectiondc.subject
Dewey Decimal GroupDDC 610 / Medicine & healthdc.subject.ddc
MeSHCholecystitisdc.subject.mesh
MeSHCholangitisdc.subject.mesh
TitleClinical presentation and incidence of anaerobic bacteria in surgically treated biliary tract infections and cholecystitisdc.title
Resource typeWissenschaftlicher Artikeldc.type
SWORD Date2021-02-03T19:15:55Zdc.date.updated
VersionpublishedVersiondc.description.version
DOIhttp://dx.doi.org/10.18725/OPARU-43527dc.identifier.doi
URNhttp://nbn-resolving.de/urn:nbn:de:bsz:289-oparu-43603-7dc.identifier.urn
GNDGallenblasenentzündungdc.subject.gnd
GNDCholangitisdc.subject.gnd
InstitutionBundeswehrkrankenhaus Ulm (BWK)uulm.affiliationSpecific
Peer reviewjauulm.peerReview
DCMI TypeTextuulm.typeDCMI
CategoryPublikationenuulm.category
In cooperation withUniversitätsklinikum der Eberhard Karls Universität Tübingenuulm.cooperation
DOI of original publication10.3390/antibiotics10010071dc.relation1.doi
Source - Title of sourceAntibioticssource.title
Source - Place of publicationMDPIsource.publisher
Source - Volume10source.volume
Source - Issue1source.issue
Source - Year2021source.year
Source - Article number71source.articleNumber
Source - eISSN2079-6382source.identifier.eissn
Open AccessDOAJ Gold, Green Publisheduulm.OA
WoS000611008800001uulm.identifier.wos
Bibliographyuulmuulm.bibliographie


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