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AuthorJin, Hongdc.contributor.author
AuthorLiu, Yuefeidc.contributor.author
AuthorSchweikert, Bernddc.contributor.author
AuthorHahman, Harrydc.contributor.author
AuthorWang, Leidc.contributor.author
AuthorImhof, Armindc.contributor.author
AuthorMuche, Rainerdc.contributor.author
AuthorKönig, Wolfgangdc.contributor.author
AuthorSteinacker, Jürgen M.dc.contributor.author
Date of accession2022-05-23T09:32:34Zdc.date.accessioned
Available in OPARU since2022-05-23T09:32:34Zdc.date.available
Date of first publication2022-01-24dc.date.issued
AbstractBackground. Acute coronary syndrome (ACS) causes pathophysiological changes in exercise capacity, N-terminal part of pro-brain natriuretic peptide (NT-proBNP), and adiponectin that impact the course of coronary artery disease and clinical outcomes after cardiac rehabilitation (CR). However, the serial changes and the relationship between the changes in these parameters for a prolonged term remain uninvestigated. Methods. Eighty-one patients with ACS underwent a three- or four-week CR program after acute care and were followed up for 12 months. Exercise capacity on a cycle ergometer and blood levels of NT-proBNP and adiponectin were determined before and after CR as well as at the 12-month follow-up. Results. Exercise capacity increased from 100 watts (in median) before CR to 138 watts after CR and 150 watts at 12 months. The NT-proBNP level (526 pg/ml before CR) remained almost unchanged after CR (557 pg/ml) and then decreased at 12 months (173 pg/ml). The adiponectin level (14.5 µg/ml before CR) increased after CR (16.0 µg/ml) and at 12 months (17.2 µg/ml). There was no significant correlation among the changes in these parameters at each observation time point. Conclusion. During the observation period from before CR to the 12-month follow-up, exercise capacity, NT-proBNP, and adiponectin underwent significant changes; however, these changes were independent from each other and not correlated linearly, and they provide complementary information in clinical practice. Thus, all these parameters should be included and determined at different time points for a prolonged period of time.dc.description.abstract
Languageendc.language.iso
PublisherUniversität Ulmdc.publisher
LicenseCC BY 4.0 Internationaldc.rights
Link to license texthttps://creativecommons.org/licenses/by/4.0/dc.rights.uri
KeywordPLASMA-CONCENTRATIONSdc.subject
KeywordARTERY-DISEASEdc.subject
KeywordENERGY-BALANCEdc.subject
Dewey Decimal GroupDDC 610 / Medicine & healthdc.subject.ddc
MeSHAcute coronary syndromedc.subject.mesh
MeSHHeart failuredc.subject.mesh
MeSHMyocardial infarctiondc.subject.mesh
MeSHCardiac rehabilitationdc.subject.mesh
MeSHNatriuretic peptide, Braindc.subject.mesh
MeSHAdultdc.subject.mesh
TitleSerial changes in exercise capacity, NT-proBNP, and adiponectin in patients with acute coronary syndrome before and after phase II rehabilitation as well as at the 12-month follow-updc.title
Resource typeWissenschaftlicher Artikeldc.type
VersionpublishedVersiondc.description.version
DOIhttp://dx.doi.org/10.18725/OPARU-43185dc.identifier.doi
URNhttp://nbn-resolving.de/urn:nbn:de:bsz:289-oparu-43261-7dc.identifier.urn
GNDAkutes Koronarsyndromdc.subject.gnd
GNDHerzfehlerdc.subject.gnd
GNDHerzinfarktdc.subject.gnd
GNDRehabilitationdc.subject.gnd
FacultyMedizinische Fakultätuulm.affiliationGeneral
InstitutionUKU. Klinik für Innere Medizin IIuulm.affiliationSpecific
InstitutionInstitut für Epidemiologie und Medizinische Biometrieuulm.affiliationSpecific
Peer reviewjauulm.peerReview
DCMI TypeTextuulm.typeDCMI
CategoryPublikationenuulm.category
In cooperation withSoutheast Universityuulm.cooperation
In cooperation withHelmholtz Zentrum Münchenuulm.cooperation
In cooperation withNanjing University of Chinese Medicineuulm.cooperation
DOI of original publication10.1155/2022/6538296dc.relation1.doi
Source - Title of sourceCardiology Research and Practicesource.title
Source - Place of publicationHindawisource.publisher
Source - Volume2022source.volume
Source - Year2022source.year
Source - Article number6538296source.articleNumber
Source - ISSN2090-8016source.identifier.issn
Source - eISSN2090-0597source.identifier.eissn
CommunityUniversität Ulm / Medizinuulm.community
WoS000771102100001uulm.identifier.wos
Bibliographyuulmuulm.bibliographie


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