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AuthorHassan, Mohammad Ahmaddc.contributor.author
Date of accession2017-03-24T10:28:37Zdc.date.accessioned
Available in OPARU since2017-03-24T10:28:37Zdc.date.available
Year of creation2014dc.date.created
Date of first publication2017-03-24dc.date.issued
AbstractBackground: Pulse oximetry is widely used in intensive care and emergency conditions to monitor arterial oxygenation and to guide oxygen therapy. Objective: To study the reliability of pulse oximetry in comparison with CO-oximetry in newborn piglets during cardiopulmonary resuscitation (CPR). Methodology: In a prospective cohort study in 30 healthy newborn piglets, cardiac arrest was induced, and thereafter each piglet received CPR for 20 min. Arterial oxygen saturation was monitored continuously by pulse oximetry (SpO2). Arterial blood was analyzed for functional oxygenation (SaO2) every 2 min. SpO 2 was compared with coinciding SaO2 values and bias considered whenever the difference (SpO 2 – SaO 2 ) was beyond ±5%. Results: Bias values were decreased at the baseline measurements (mean: 2.5 ± 4.6%) with higher precision and accuracy compared with values across the experiment. Two minutes after cardiac arrest, there was a marked decrease in precision and accuracy as well as an increase in bias up to 13 ± 34%, reaching a maximum of 45.6 ± 28.3% after 10 min over a mean SaO 2 range of 29–58%. Conclusion: Pulse oximetry showed increased bias and decreased accuracy and precision during CPR in a model of neonatal cardiac arrest. We recommend further studies to clarify the exact mechanisms of these false readings to improve reliability of pulse oximetry during the marked desaturation and hypoperfusion found during CPR.dc.description.abstract
Languageendc.language.iso
PublisherUniversität Ulmdc.publisher
LicenseStandarddc.rights
Link to license texthttps://oparu.uni-ulm.de/xmlui/license_v3dc.rights.uri
KeywordKardiopulmonale Reanimationdc.subject
Dewey Decimal GroupDDC 610 / Medicine & healthdc.subject.ddc
MeSHCardiopulmonary resucitationdc.subject.mesh
MeSHOximetrydc.subject.mesh
MeSHIntensive care, neonataldc.subject.mesh
MeSHModels, animaldc.subject.mesh
TitleAccuracy of pulse oximetry during neonatal resuscitationdc.title
Resource typeDissertationdc.type
Date of acceptance2016-10-21dcterms.dateAccepted
RefereeMuth, Claus-Martindc.contributor.referee
RefereeMeißner, Peterdc.contributor.referee
RefereeHummler, Helmutdc.contributor.referee
DOIhttp://dx.doi.org/10.18725/OPARU-4284dc.identifier.doi
PPN883628201dc.identifier.ppn
URNhttp://nbn-resolving.de/urn:nbn:de:bsz:289-oparu-4323-7dc.identifier.urn
GNDWiederbelebungdc.subject.gnd
GNDOxymetriedc.subject.gnd
FacultyMedizinische Fakultätuulm.affiliationGeneral
InstitutionUKU. Klinik für Anästhesiologieuulm.affiliationSpecific
InstitutionUKU. Klinik für Kinder- und Jugendmedizinuulm.affiliationSpecific
Shelfmark print versionW: W-H 15.049uulm.shelfmark
Grantor of degreeMedizinische Fakultätuulm.thesisGrantor
DCMI TypeTextuulm.typeDCMI
TypeErstveröffentlichunguulm.veroeffentlichung
CategoryPublikationenuulm.category
University Bibliographyjauulm.unibibliographie


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