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AuthorRadtke, Franziskadc.contributor.author
Date of accession2016-09-16T08:56:01Zdc.date.accessioned
Available in OPARU since2016-09-16T08:56:01Zdc.date.available
Year of creation2016dc.date.created
Date of first publication2016-09-16dc.date.issued
AbstractHuman Cytomegalovirus (HCMV) is a ubiquitous herpesvirus causing high morbidity in individuals with an impaired immune defense. The two major types of monocyte-derived macrophages in vitro (MΦ), M1-MΦ and M2-MΦ, are unequally susceptible to infection by HCMV. Anti-inflammatory, anti-immunogenic M2-MΦ get infected about twofold compared to pro-inflammatory, immunogenic M1-MΦ. In this study differences between the two cell subsets regarding early HCMV infection were examined. The hypothesis in this study was particularly, that dissimilar expression of possible entry receptors or intrinsic restriction factors of viral infection define the different susceptibility.dc.description.abstract
Languageendc.language.iso
PublisherUniversität Ulmdc.publisher
LicenseStandarddc.rights
Link to license texthttps://oparu.uni-ulm.de/xmlui/license_v3dc.rights.uri
KeywordCMVdc.subject
KeywordInfectivity ratedc.subject
Dewey Decimal GroupDDC 610 / Medicine & healthdc.subject.ddc
MeSHVirologydc.subject.mesh
MeSHCytomegalovirusdc.subject.mesh
MeSHMacrophagesdc.subject.mesh
TitleComparison of M1- and M2-monocyte derived macrophages (MΦ) in early events of human cytomegalovirus infectiondc.title
Resource typeDissertationdc.type
Date of acceptance2016-07-08dcterms.dateAccepted
RefereeMertens, Thomasdc.contributor.referee
RefereeKirchhoff, Frankdc.contributor.referee
DOIhttp://dx.doi.org/10.18725/OPARU-4103dc.identifier.doi
PPN1658696212dc.identifier.ppn
URNhttp://nbn-resolving.de/urn:nbn:de:bsz:289-oparu-4142-1dc.identifier.urn
GNDVirologiedc.subject.gnd
GNDCytomegalie-Virusdc.subject.gnd
GNDMakrophagedc.subject.gnd
FacultyMedizinische Fakultätuulm.affiliationGeneral
InstitutionUKU. Institut für Virologieuulm.affiliationSpecific
InstitutionUKU. Institut für Molekulare Virologieuulm.affiliationSpecific
Shelfmark print versionW: W-H 14.854uulm.shelfmark
Grantor of degreeMedizinische Fakultätuulm.thesisGrantor
DCMI TypeTextuulm.typeDCMI
TypeErstveröffentlichunguulm.veroeffentlichung
CategoryPublikationenuulm.category
Bibliographyuulmuulm.bibliographie


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