A Conformational Change of Complement C5 Is Required for Thrombin-Mediated Cleavage, Revealed by a Novel Ex Vivo Human Whole Blood Model Preserving Full Thrombin Activity

Erstveröffentlichung
2021Authors
Nilsson, Per H.
Johnson, Christina
Quach, Quang Huy
Macpherson, Alex
Durrant, Oliver
Wissenschaftlicher Artikel
Published in
Journal of Immunology ; 207 (2021), 6. - S. 1641-1651. - ISSN 0022-1767. - eISSN 1550-6606
Link to publication
https://dx.doi.org/10.4049/jimmunol.2001471Institutions
UKU. Klinik für Unfall-, Hand-, Plastische- und WiederherstellungschirurgieSubject headings
[Free subject headings]: IN-VITRO ACTIVATION | 5TH COMPONENT | ALTERNATIVE PATHWAY | MONOCLONAL-ANTIBODY | COAGULATION | SYSTEM | PURIFICATION | PLASMA | PRODUCTS | ACIDOSIS[DDC subject group]: DDC 610 / Medicine & health