SHANK2 Mutations Result in Dysregulation of the ERK1/2 Pathway in Human Induced Pluripotent Stem Cells-Derived Neurons and Shank2(-/-) Mice

Erstveröffentlichung
2021Authors
Lutz, Anne-Kathrin
Arevalo, Andrea Perez
Ioannidis, Valentin
Stirmlinger, Nadine
Demestre, Maria
Wissenschaftlicher Artikel
Published in
Frontiers in Molecular Neuroscience ; 14 (2021). - Art.-Nr. 773571. - ISSN 1662-5099
Link to publication
https://dx.doi.org/10.3389/fnmol.2021.773571Faculties
Medizinische FakultätInstitutions
DZNE UlmInstitut für Anatomie und Zellbiologie
Subject headings
[Free subject headings]: SHANK2 | hiPSCs | ERK1 | 2 | neurodevelopment | ASD | AUTISM SPECTRUM DISORDER | POSTSYNAPTIC DENSITY | PROTEIN EXPRESSION | BINDING-PROTEIN | MOUSE MODEL | SYNAPSE | FAMILY | GENE | PATHOGENESIS | INHIBITION[DDC subject group]: DDC 570 / Life sciences