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AuthorWang, Yandc.contributor.author
Date of accession2021-12-09T12:55:00Zdc.date.accessioned
Available in OPARU since2021-12-09T12:55:00Zdc.date.available
Year of creation2021dc.date.created
Date of first publication2021-12-09dc.date.issued
AbstractLignocellulosic biomass is the most abundant bio-resource on earth containing carbohydrates polymers cellulose, hemicellulose and lignin. With a number of methods including pretreatment and hydrolysis, lignocellulose-derived hydrolysates containing D-glucose, D-xylose, L-arabinose, and further sugars can be obtained. The hydrolysates consisting fermentable sugars typically display a high degree of variation depending on both the biomass source materials and process conditions, resulting in different compositions such as various concentrations of monosaccharide sugars and inhibitors. The fermentable sugars in lignocellulosic hydrolysates have attracted many people’s attention all over the world, because these fermentable sugars have a great potential to be used by microorganisms as a sole carbon source for the growth and production of bioproducts. To date, several bioproducts such as biofuels, chemicals and many high value-added products have been already investigated and produced, and the application field is still expanding. However, one of the key obstacles is that not all the microorganisms have the ability to metabolize all the different sugars in hydrolysates. Most of the known microorganisms only utilize D-glucose as the sole carbon source, which results in the energy loss of lignocellulosic biomass. Another obstacle is that the inhibitors formed during hydrolysis, limit the efficient usage of hydrolysates as a carbon source for biotechnological conversion. To further investigate and overcome these obstacles, in this Ph.D. thesis, the following research works have been examined and summarized: 1) Investigation the sugar utilization of Escherichia coli strains and the production of αs1-casein proteins based on lignocellulosic hydrolysates. 2) Metabolic engineering of Pseudomonas putida KT2440 as microbial biocatalyst for the utilization of D-xylose and L-arabinose. 3) Evaluation of different lignocellulosic hydrolysates as substrates for engineered P. putida KT2440 and the inhibitory effectiveness on P. putida KT2440.dc.description.abstract
Languageendc.language.iso
PublisherUniversität Ulmdc.publisher
Has partYan Wang, Dennis Kubiczek, Felix Horlamus, Heinz Fabian Raber, Till Hennecke, Daniel Einfalt, Marius Henkel, Rudolf Hausmann, Andreas Wittgens, Frank Rosenau. Bioconversion of lignocellulosic ‘waste’ to high value food proteins: recombinant production of bovine and human αS1-casein based on wheat straw lignocellulose. GCB Bioenergy.2021; 13:640-655. doi: 10.1111/gcbb.12791dc.relation.haspart
Has partFelix Hoalamus, Yan Wang, David Steinbach, Maliheh Vahidinasab, Andreas Wittgens, Frank Rosenau, Marius Henkel, Rudolf Hausmann. Potential of biotechnological conversion of lignocellulose hydrolyzates by Pseudomonas putida KT2440 as a model organism for a bio-based economy. GCB Bioenergy.2019; 00:1-14. doi: 10.1111/gcbb.12647dc.relation.haspart
Has partYan Wang, Felix Horlamus, Marius Henkel, Filip Kovacic, Sandra Schläfle, Rudolf Hausmann, Andreas Wittgens, Frank Rosenau. Growth of engineered Pseudomonas putida KT2440 on glucose, xylose and arabinose: Hemicellulose hydrolysates and their major sugars as sustainable carbon sources. GCB Bioenergy.2019; 11: 249-259. doi: 10.1111/gcbb.12590dc.relation.haspart
LicenseCC BY 4.0 Internationaldc.rights
Link to license texthttps://creativecommons.org/licenses/by/4.0/dc.rights.uri
KeywordLignocellulosic hydrolysatesdc.subject
KeywordBioconversiondc.subject
KeywordMetabolic engineeringdc.subject
KeywordMicrobial biocatalystdc.subject
Dewey Decimal GroupDDC 540 / Chemistry & allied sciencesdc.subject.ddc
LCSHBiomassdc.subject.lcsh
LCSHMicrobiologydc.subject.lcsh
TitleMicrobial utilization and bioconversion of lignocellulosic hydrolysatesdc.title
Resource typeDissertationdc.type
Date of acceptance2021-07-13dcterms.dateAccepted
RefereeRosenau, Frankdc.contributor.referee
RefereeGottschalk, Kay-Eberharddc.contributor.referee
DOIhttp://dx.doi.org/10.18725/OPARU-40294dc.identifier.doi
PPN1781994986dc.identifier.ppn
URNhttp://nbn-resolving.de/urn:nbn:de:bsz:289-oparu-40370-6dc.identifier.urn
GNDBiomassedc.subject.gnd
FacultyFakultät für Naturwissenschaftenuulm.affiliationGeneral
InstitutionInstitut für Pharmazeutische Biotechnologieuulm.affiliationSpecific
InstitutionInstitut für Experimentelle Physikuulm.affiliationSpecific
Grantor of degreeFakultät für Naturwissenschaftenuulm.thesisGrantor
DCMI TypeTextuulm.typeDCMI
CategoryPublikationenuulm.category
Bibliographyuulmuulm.bibliographie


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