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AuthorLaptinskaya, Dariadc.contributor.author
AuthorFissler, Patrickdc.contributor.author
AuthorKüster, Olivia Carolinedc.contributor.author
AuthorWischniowski, Jakobdc.contributor.author
AuthorThurm, Frankadc.contributor.author
AuthorElbert, Thomasdc.contributor.author
AuthorArnim, Christine vondc.contributor.author
AuthorKolassa, Iris‐Tatjanadc.contributor.author
Date of accession2021-11-03T14:20:06Zdc.date.accessioned
Available in OPARU since2021-11-03T14:20:06Zdc.date.available
Date of first publication2019-12-16dc.date.issued
AbstractQuantitative electroencephalography (EEG) provides useful information about neurophysiological health of the aging brain. Current studies investigating EEG coherence and power for specific brain areas and frequency bands have yielded inconsistent results. This study assessed EEG coherence and power indices at rest measured over the whole skull and for a wide frequency range as global EEG markers for cognition in a sample at risk for dementia. Since global markers are more reliable and less error‐prone than region‐ and frequency‐specific indices they might help to overcome previous inconsistencies. Global EEG coherence (1–30 Hz) and an EEG slowing score were assessed. The EEG slowing score was calculated by low‐frequency power (1–8 Hz) divided by high‐frequency power (9–30 Hz). In addition, the prognostic value of the two EEG indices for cognition and cognitive decline was assessed in a 5‐year follow‐up pilot study. Baseline global coherence correlated positively with cognition at baseline, but not with cognitive decline or with cognition at the 5‐year follow‐up. The EEG slowing ratio showed no significant association, neither with cognition at baseline or follow‐up, nor with cognitive decline over a period of 5 years. The results indicate that the resting state global EEG coherence might be a useful and easy to assess electrophysiological correlate for neurocognitive health in older adults at risk for dementia. Because of the small statistical power for the follow‐up analyses, the prognostic value of global coherence could not be determined in the present study. Future studies should assess its prognostic value with larger sample sizes.dc.description.abstract
AbstractThe study introduces global coherence across all regions and a wide range of frequency bands as a robust electrophysiological marker for cognition in older adults with a higher risk for developing dementia. In addition, it presents longitudinal electrophysiological data for coherence‐cognition relationships. The study results suggest that global EEG coherence may be currently of higher benefit in research and in clinical application than region‐ and frequency‐specific coherence measures.dc.description.abstract
Languageendc.language.iso
PublisherUniversität Ulmdc.publisher
LicenseCC BY 4.0 Internationaldc.rights
Link to license texthttps://creativecommons.org/licenses/by/4.0/dc.rights.uri
KeywordAlzheimer’s diseasedc.subject
Keywordcoherencedc.subject
Keywordfunctional connectivitydc.subject
Keywordspectral powerdc.subject
Dewey Decimal GroupDDC 570 / Life sciencesdc.subject.ddc
Dewey Decimal GroupDDC 610 / Medicine & healthdc.subject.ddc
MeSHAlzheimer diseasedc.subject.mesh
MeSHElectroencephalographydc.subject.mesh
MeSHCognitiondc.subject.mesh
TitleGlobal EEG coherence as a marker for cognition in older adults at risk for dementiadc.title
Resource typeWissenschaftlicher Artikeldc.type
SWORD Date2020-12-09T19:33:47Zdc.date.updated
VersionpublishedVersiondc.description.version
DOIhttp://dx.doi.org/10.18725/OPARU-39516dc.identifier.doi
URNhttp://nbn-resolving.de/urn:nbn:de:bsz:289-oparu-39592-4dc.identifier.urn
GNDAlzheimerkrankheitdc.subject.gnd
GNDElektroencephalographiedc.subject.gnd
FacultyFakultät für Ingenieurwissenschaften, Informatik und Psychologieuulm.affiliationGeneral
InstitutionInstitut für Psychologie und Pädagogikuulm.affiliationSpecific
InstitutionUKU. Klinik für Neurologieuulm.affiliationSpecific
Peer reviewjauulm.peerReview
DCMI TypeTextuulm.typeDCMI
CategoryPublikationenuulm.category
In cooperation withGeorg-August-Universität Göttingenuulm.cooperation
In cooperation withUniversität Konstanzuulm.cooperation
In cooperation withTechnische Universität Dresdenuulm.cooperation
DOI of original publication10.1111/psyp.13515dc.relation1.doi
Source - Title of sourcePsychophysiologysource.title
Source - Place of publicationWileysource.publisher
Source - Volume57source.volume
Source - Issue4source.issue
Source - Year2020source.year
Source - Article numbere13515source.articleNumber
Source - ISSN1469-8986source.identifier.issn
Source - eISSN1469-8986source.identifier.eissn
Bibliographyuulmuulm.bibliographie


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