ORAI1-mediated calcium influx is required for human cytotoxic lymphocyte degranulation and target cell lysis

Erstveröffentlichung
2011Authors
Maul-Pavicic, Andrea
Chiang, Samuel C. C.
Rensing-Ehl, Anne
Jessen, Birthe
Fauriat, Cyril
Wissenschaftlicher Artikel
Published in
Proceedings of the National Academy of Sciences of the United States of America ; 108 (2011), 8. - S. 3324-3329. - ISSN 0027-8424. - eISSN 1091-6490
Link to publication
https://dx.doi.org/10.1073/pnas.1013285108Institutions
UKU. Institut für TransfusionsmedizinInstitut für Klinische Transfusionsmedizin und Immungenetik Ulm gGmbH (IKT)
Subject headings
[Free subject headings]: primary immunodeficiency | cytotoxic lymphocytes | lytic granules | perforin | MICROTUBULE-ORGANIZING CENTER | ACTIVATED T-CELLS | MICE LACKING | EXPRESSION | POLARIZATION | MUTATION | ORAI1 | STIM1 | IMMUNODEFICIENCY | CYTOSKELETON[DDC subject group]: DDC 570 / Life sciences | DDC 610 / Medicine & health