ORAI1-mediated calcium influx is required for human cytotoxic lymphocyte degranulation and target cell lysis
Erstveröffentlichung
2011
Wissenschaftlicher Artikel
Published in
Proceedings of the National Academy of Sciences of the United States of America ; 108 (2011), 8. - S. 3324-3329. - ISSN 0027-8424. - eISSN 1091-6490
Link to publication
https://dx.doi.org/10.1073/pnas.1013285108Institutions
UKU. Institut für TransfusionsmedizinInstitut für Klinische Transfusionsmedizin und Immungenetik Ulm gGmbH (IKT)
Subject headings
[Free subject headings]: primary immunodeficiency | cytotoxic lymphocytes | lytic granules | perforin | MICROTUBULE-ORGANIZING CENTER | ACTIVATED T-CELLS | MICE LACKING | EXPRESSION | POLARIZATION | MUTATION | ORAI1 | STIM1 | IMMUNODEFICIENCY | CYTOSKELETON[DDC subject group]: DDC 570 / Life sciences | DDC 610 / Medicine & health