Factors affecting the detection and quantification of mitochondrial point heteroplasmy using Sanger sequencing and SNaPshot minisequencing

Erstveröffentlichung
2011Authors
Naue, Jana
Saenger, Timo
Schmidt, Ulrike
Klein, Rachel
Lutz-Bonengel, Sabine
Wissenschaftlicher Artikel
Published in
International Journal of Legal Medicine ; 125 (2011), 3. - S. 427-436. - ISSN 0937-9827. - eISSN 1437-1596
Link to publication
https://dx.doi.org/10.1007/s00414-011-0549-6Institutions
UKU. Institut für RechtsmedizinSubject headings
[Free subject headings]: Mitochondrial DNA | Sequence heteroplasmy detection | Sanger sequencing | Minisequencing | SNaPshot | Artificial mixtures | MTDNA CONTROL REGION | DNA HETEROPLASMY | MUTATION | REMAINS | PCR | IDENTIFICATION | INCREASES | FREQUENCY | LENGTH | ASSAY[DDC subject group]: DDC 610 / Medicine & health