Adenovirus vector-based in vitro neuronal cell model for Huntington's disease with human disease-like differential aggregation and degeneration

Erstveröffentlichung
2012
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Wissenschaftlicher Artikel


Authors
Dong, Xiaomin
Zong, Shan
Witting, Anke
Lindenberg, Katrin S.
Kochanek, Stefan
et al.
Institutions
UKU. Abteilung für Gentherapie
UKU. Klinik für Neurologie
Published in
Journal of Gene Medicine ; 14 (2012), 7. - S. 468-481. - ISSN 1099-498X. - eISSN 1521-2254
Link to publication
https://dx.doi.org/10.1002/jgm.2641
Keywords
adenovirus vector; cortical neurons; Huntingtin; Huntington's disease; model; striatal neurons; N-TERMINAL FRAGMENTS; LENGTH MUTANT HUNTINGTIN; INTRANUCLEAR INCLUSIONS; CASPASE CLEAVAGE; EXPRESSION; GENE; NUCLEAR; NEURODEGENERATION; LOCALIZATION; PROTEOLYSIS
Dewey Decimal Group
DDC 570 / Life sciences
DDC 610 / Medicine & health
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