Adenovirus vector-based in vitro neuronal cell model for Huntington's disease with human disease-like differential aggregation and degeneration

Erstveröffentlichung
2012Authors
Dong, Xiaomin
Zong, Shan
Witting, Anke
Lindenberg, Katrin S.
Kochanek, Stefan
Wissenschaftlicher Artikel
Published in
Journal of Gene Medicine ; 14 (2012), 7. - S. 468-481. - ISSN 1099-498X. - eISSN 1521-2254
Link to publication
https://dx.doi.org/10.1002/jgm.2641Institutions
UKU. Abteilung für GentherapieUKU. Klinik für Neurologie
Subject headings
[Free subject headings]: adenovirus vector | cortical neurons | Huntingtin | Huntington's disease | model | striatal neurons | N-TERMINAL FRAGMENTS | LENGTH MUTANT HUNTINGTIN | INTRANUCLEAR INCLUSIONS | CASPASE CLEAVAGE | EXPRESSION | GENE | NUCLEAR | NEURODEGENERATION | LOCALIZATION | PROTEOLYSIS[DDC subject group]: DDC 570 / Life sciences | DDC 610 / Medicine & health