Prognostic and predictive impact of genetic markers in patients with CLL treated with obinutuzumab and venetoclax

Erstveröffentlichung
2020Authors
Tausch, Eugen
Schneider, Christof
Robrecht, Sandra
Zhang, Can
Dolnik, Anna
Wissenschaftlicher Artikel
Published in
Blood ; 135 (2020), 26. - S. 2402-2412. - ISSN 0006-4971. - eISSN 1528-0020
Link to publication
https://dx.doi.org/10.1182/blood.2019004492Institutions
UKU. Klinik für Innere Medizin IIIDFG Project THU
SFB 1074 / Experimentelle Modelle und klinische Translation bei Leukämien / DFG / 217328187
Subject headings
[Free subject headings]: VenG was superior to GClb across different genetic subgroups | but del(17p) and mutated TP53 remain as adverse prognostic markers | Unmutated IGHV is a predictive factor for particular benefit from venetoclax and obinutuzumab | CHRONIC LYMPHOCYTIC-LEUKEMIA | INDEPENDENT PREDICTOR | CLINICAL IMPACT | MUTATIONS | SURVIVAL | NOTCH1 | PROGRESSION | IBRUTINIB | SF3B1 | BIRC3[DDC subject group]: DDC 610 / Medicine & health