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AuthorLunkenheimer, Frederikedc.contributor.author
AuthorDomhardt, Matthiasdc.contributor.author
AuthorGeirhos, Agnesdc.contributor.author
AuthorKilian, Reinholddc.contributor.author
AuthorMüller-Stierlin, Annabel Sandradc.contributor.author
AuthorHoll, Reinharddc.contributor.author
AuthorMeissner, Thomasdc.contributor.author
AuthorMinden, Kirstendc.contributor.author
AuthorMoshagen, Mortendc.contributor.author
AuthorRanz, Ramonadc.contributor.author
AuthorSachser, Cedricdc.contributor.author
AuthorStaab, Dorisdc.contributor.author
AuthorWarschburger, Petradc.contributor.author
AuthorBaumeister, Haralddc.contributor.author
Date of accession2020-09-07T16:02:53Zdc.date.accessioned
Available in OPARU since2020-09-07T16:02:53Zdc.date.available
Date of first publication2020-03-12dc.date.issued
AbstractBackground: Adolescents and young adults (AYA) with chronic somatic conditions have an increased risk of comorbid depression and anxiety symptoms. Internet- and mobile-based cognitive behavioural therapy (iCBT) might be one possibility to extend the access to evidence-based treatments. Studies suggest that guided iCBT can reduce anxiety and depression symptoms in AYA. However, little is known about the effectiveness of iCBT for AYA with chronic somatic conditions and comorbid symptoms of anxiety and/or depression in routine care. Evidence on the (cost-)effectiveness of iCBT is essential for its implementation in health care. Objectives and methods: This multicentre two-armed randomized controlled trial (RCT) aims to evaluate the (cost-) effectiveness of guided iCBT (youthCOACHCD) in addition to treatment as usual (TAU) compared to enhanced treatment as usual (TAU+) in AYA aged 12–21 years with one of three chronic somatic conditions (type 1 diabetes, cystic fibrosis, or juvenile idiopathic arthritis). AYA with one of the chronic somatic conditions and elevated symptoms of anxiety or depression (Patient Health Questionnaire [PHQ-9] and/or Generalized Anxiety Disorder [GAD-7] Screener score ≥ 7) will be eligible for inclusion. We will recruit 212 patients (2 × n = 106) in routine care through three German patient registries. Assessments will take place at baseline and at 6 weeks, 3 months, 6 months, and 12 months post-randomization. The primary outcome will be combined depression and anxiety symptom severity as measured with the PHQ Anxiety and Depression Scale. Secondary outcomes will include health-related quality of life, coping strategies, self-efficacy, stress-related personal growth, social support, behavioural activation, adjustment and trauma-related symptoms, automatic thoughts, intervention satisfaction, working alliance, and Internet usage. The cost-effectiveness will be determined, and potential moderators and mediators of intervention effects will be explored. Discussion: iCBT might implicate novel ways to increase the access to evidence-based interventions in this specific population. The distinct focus on effectiveness and cost-effectiveness of youthCOACHCD in patients with chronic somatic conditions, as well as intervention safety, will most likely provide important new insights in the field of paediatric e-mental health. A particular strength of the present study is its implementation directly into routine collaborative health care. As such, this study will provide important insights for health care policy and stakeholders and indicate how iCBT can be integrated into existing health care systems.dc.description.abstract
Languageendc.language.iso
PublisherUniversität Ulmdc.publisher
LicenseCC BY 4.0 Internationaldc.rights
Link to license texthttps://creativecommons.org/licenses/by/4.0/dc.rights.uri
KeywordAYAdc.subject
KeywordChronic somatic conditionsdc.subject
KeywordRCTdc.subject
KeywordInternet- and mobile-based interventions, ICBTdc.subject
Dewey Decimal GroupDDC 610 / Medicine & healthdc.subject.ddc
MeSHDepressiondc.subject.mesh
MeSHAnxiety disordersdc.subject.mesh
MeSHCost of illnessdc.subject.mesh
MeSHAdolescentdc.subject.mesh
MeSHYoung adultdc.subject.mesh
MeSHCognitive behavioral therapy; Methodsdc.subject.mesh
MeSHChronic disease; Therapydc.subject.mesh
MeSHMultiple chronic conditions; Prevention and controldc.subject.mesh
TitleEffectiveness and cost-effectiveness of guided internet- and mobile-based CBT for adolescents and young adults with chronic somatic conditions and comorbid depression and anxiety symptoms (youthCOACHcd) : study protocol for a multicentre randomized controlled trialdc.title
Resource typeWissenschaftlicher Artikeldc.type
VersionpublishedVersiondc.description.version
DOIhttp://dx.doi.org/10.18725/OPARU-33030dc.identifier.doi
URNhttp://nbn-resolving.de/urn:nbn:de:bsz:289-oparu-33092-7dc.identifier.urn
GNDAngststörungdc.subject.gnd
GNDChronisch Krankerdc.subject.gnd
GNDVerhaltenstherapiedc.subject.gnd
GNDSekundärkrankheitdc.subject.gnd
FacultyFakultät für Ingenieurwissenschaften, Informatik und Psychologieuulm.affiliationGeneral
InstitutionInstitut für Psychologie und Pädagogikuulm.affiliationSpecific
InstitutionUKU. Klinik für Psychiatrie und Psychotherapie IIuulm.affiliationSpecific
InstitutionInstitut für Epidemiologie und Medizinische Biometrieuulm.affiliationSpecific
InstitutionUKU. Klinik für Kinder- und Jugendpsychiatrie/Psychotherapieuulm.affiliationSpecific
Peer reviewjauulm.peerReview
DCMI TypeTextuulm.typeDCMI
CategoryPublikationenuulm.category
In cooperation withHeinrich-Heine-Universität Düsseldorfuulm.cooperation
In cooperation withCharité – Universitätsmedizin Berlinuulm.cooperation
In cooperation withDeutsches Rheuma-Forschungszentrum (DRFZ)uulm.cooperation
In cooperation withUniversität Potsdamuulm.cooperation
Corporate editorCOACH-Projektdc.contributor.editorInstitution
DOI of original publication10.1186/s13063-019-4041-9dc.relation1.doi
Source - Title of sourceTrialssource.title
Source - Place of publicationBMCsource.publisher
Source - Volume21source.volume
Source - Issue1source.issue
Source - Year2020source.year
Source - Article number253source.articleNumber
Source - eISSN1745-6215source.identifier.eissn
FundingAbbVieuulm.funding
FundingChugaiuulm.funding
FundingNovartisuulm.funding
FundingCOACH – Patientenzentrierte interdisziplinäre Gesundheitsversorgung bei chronisch kranken Jugendlichen / BMBF [01GL1740A]uulm.funding
FundingKlinische Studie zur psychologischen Onlineintervention / BMBF [01GL1740E]uulm.funding
Bibliographyuulmuulm.bibliographie
Is Supplemented Byhttps://trialsjournal.biomedcentral.com/articles/10.1186/s13063-019-4041-9#Sec28dc.relation.isSupplementedBy


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