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AuthorLaubner, Katharinadc.contributor.author
AuthorPrinz, Nicoledc.contributor.author
AuthorBrückel, Joachimdc.contributor.author
AuthorSerwas, Andreasdc.contributor.author
AuthorAltmeier, Marcusdc.contributor.author
AuthorWelp, Reinharddc.contributor.author
AuthorKrakow, Dietmardc.contributor.author
AuthorGroß, Felixdc.contributor.author
AuthorBollow, Estherdc.contributor.author
AuthorSeufert, Jochendc.contributor.author
AuthorHoll, Reinharddc.contributor.author
AuthorDPV Initiativedc.contributor.author
Date of accession2020-07-31T07:15:22Zdc.date.accessioned
Available in OPARU since2020-07-31T07:15:22Zdc.date.available
Date of first publication2018-07-06dc.date.issued
AbstractIntroduction: Bariatric surgery is a well-established treatment option for serious obesity and concomitant type 2 diabetes mellitus (T2DM). In this analysis, we investigated predictors for bariatric surgery in everyday clinical practice. Materials and Methods: In the DPV-registry, patients with T2DM from Germany and Austria treated by bariatric surgery were compared to non-surgery controls by descriptive statistics and regression analysis. Results: Among 277,862 patients with T2DM, 0.07% underwent bariatric surgery. Surgery patients were predominantly female [61.20%], younger [median age (Q1;Q3) 54.74 (47.40;61.61) vs. 70.04 (60.36;77.58) years] and had a longer diabetes duration [11.21 (7.15;17.93) vs. 8.36 (2.94;14.91) years]. They had a higher BMI [40.02 vs. 30.61 kg/m2, adjusted p<0.0001] and a slightly lower HbA1c [7.25 vs. 7.56%, adjusted p< 0.05]. There was a trend using more often insulin therapy (52.79 vs.50.08%, n.s.) with no difference in insulin dose/kg × day [0.56 vs. 0.58, n.s.]. Sleeve gastrectomy was performed most frequently, followed by Roux-en-Y gastric bypass, gastric banding, gastric balloon and others. A 2-year follow-up data in 29 patients demonstrated significant reductions in BMI [45.23 to 38.00 kg/m2, p< 0.005] and HbA1c [7.98 to 6.98%, p<0.005],and a trend for reduced insulin requirements [62.07 vs. 44.83%, n.s.]. Conclusion: Despite favourable 2-year outcomes, bariatric surgery is still used rarely in patients with T2DM and obesity. BMI rather than metabolic control seems to represent the major selector for or against bariatric surgery in T2DM.dc.description.abstract
Languageendc.language.iso
PublisherUniversität Ulmdc.publisher
LicenseStandarddc.rights
Link to license texthttps://oparu.uni-ulm.de/xmlui/license_v3dc.rights.uri
KeywordMedical treatmentdc.subject
Dewey Decimal GroupDDC 610 / Medicine & healthdc.subject.ddc
MeSHDiabetes mellitus, Type 2dc.subject.mesh
MeSHBariatric surgerydc.subject.mesh
MeSHTherapeuticsdc.subject.mesh
TitleComparative characteristics of patients with type 2 diabetes mellitus treated by bariatric surgery versus medical treatment: a multicentre analysis of 277,862 patients from the German/Austrian DPV databasedc.title
Resource typeWissenschaftlicher Artikeldc.type
VersionacceptedVersiondc.description.version
DOIhttp://dx.doi.org/10.18725/OPARU-32430dc.identifier.doi
URNhttp://nbn-resolving.de/urn:nbn:de:bsz:289-oparu-32492-4dc.identifier.urn
GNDDiabetes mellitus Typ 2dc.subject.gnd
GNDFettsuchtdc.subject.gnd
GNDMagenchirurgiedc.subject.gnd
GNDTherapiedc.subject.gnd
FacultyMedizinische Fakultätuulm.affiliationGeneral
InstitutionInstitut für Epidemiologie und medizinische Biometrieuulm.affiliationSpecific
Peer reviewjauulm.peerReview
DCMI TypeTextuulm.typeDCMI
CategoryPublikationenuulm.category
In cooperation withAlbert-Ludwigs-Universität Freiburguulm.cooperation
In cooperation withDeutsches Zentrum für Diabetesforschung (DZD)uulm.cooperation
In cooperation withOberschwabenklinik Wangenuulm.cooperation
In cooperation withHerz-Jesu-Krankenhaus Münster-Hiltrupuulm.cooperation
In cooperation withDiabeteszentrum am Klinikum Dortmunduulm.cooperation
In cooperation withKnappschaftskrankenhaus Bottropuulm.cooperation
In cooperation withDiabeteszentrum Forchheimuulm.cooperation
In cooperation withDiabetologische Schwerpunktpraxisuulm.cooperation
Is Supplemented Byhttps://link.springer.com/article/10.1007/s11695-018-3380-z#Sec2uulm.relation.isSupplementedBy
DOI of original publication10.1007/s11695-018-3380-zdc.relation1.doi
Source - Title of sourceObesity Surgerysource.title
Source - Place of publicationSpringersource.publisher
Source - Volume28source.volume
Source - Issue11source.issue
Source - Year2018source.year
Source - From page3366source.fromPage
Source - To page3373source.toPage
Source - ISSN0960-8923source.identifier.issn
Source - eISSN1708-0428source.identifier.eissn
EU projectDIRECT / DIabetes REsearCh on patient sTratification / EC / FP7 / 115317uulm.projectEU
FundingBMBF / Kompetenznetz Diabetes mellitus, Germany [FKZ 01GI1106]uulm.funding
FundingEuropean Foundation for the Study of Diabetes (EFSD)uulm.funding
FundingGerman Diabetes Association (DDG)uulm.funding
University Bibliographyjauulm.unibibliographie


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