An ex vivo loop system models the toxicity and efficacy of PEGylated and unmodified adenovirus serotype 5 in whole human blood

Erstveröffentlichung

2010

Authors

Danielsson, Angelika

Elgue, G.

Nilsson, Britt-Marie

Nilsson, Bo

Lambris, John D.

et al.

Wissenschaftlicher Artikel

Published in

Gene Therapy ; 17 (2010), 6. - S. 752-762. - ISSN 0969-7128. - eISSN 1476-5462

Link to publication

https://dx.doi.org/10.1038/gt.2010.18

Institutions

UKU. Abteilung für Gentherapie

Subject headings

[Free subject headings]: human blood model | PEGylated adenovirus | immune response | cytokines | complement system | cell adhesion | POLYETHYLENE-GLYCOL MODIFICATION | INNATE IMMUNE-RESPONSES | PHASE-I TRIAL | ONCOLYTIC ADENOVIRUS | NEUTRALIZING ANTIBODIES | HUMAN-COMPLEMENT | GENE-TRANSFER | PROSTATE-CANCER | CLINICAL-TRIALS | VECTORS
[DDC subject group]: DDC 570 / Life sciences | DDC 610 / Medicine & health

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