An ex vivo loop system models the toxicity and efficacy of PEGylated and unmodified adenovirus serotype 5 in whole human blood

Erstveröffentlichung
2010Authors
Danielsson, Angelika
Elgue, G.
Nilsson, Britt-Marie
Nilsson, Bo
Lambris, John D.
Wissenschaftlicher Artikel
Published in
Gene Therapy ; 17 (2010), 6. - S. 752-762. - ISSN 0969-7128. - eISSN 1476-5462
Link to publication
https://dx.doi.org/10.1038/gt.2010.18Institutions
UKU. Abteilung für GentherapieSubject headings
[Free subject headings]: human blood model | PEGylated adenovirus | immune response | cytokines | complement system | cell adhesion | POLYETHYLENE-GLYCOL MODIFICATION | INNATE IMMUNE-RESPONSES | PHASE-I TRIAL | ONCOLYTIC ADENOVIRUS | NEUTRALIZING ANTIBODIES | HUMAN-COMPLEMENT | GENE-TRANSFER | PROSTATE-CANCER | CLINICAL-TRIALS | VECTORS[DDC subject group]: DDC 570 / Life sciences | DDC 610 / Medicine & health