Differential methylation in CN-AML preferentially targets non-CGI regions and is dictated by DNMT3A mutational status and associated with predominant hypomethylation of HOX genes

Erstveröffentlichung

2014

Authors

Qu, Ying

Lennartsson, Andreas

Gaidzik, Verena Ingeborg

Deneberg, Stefan

Karimi, Mohsen

et al.

Wissenschaftlicher Artikel

Published in

Epigenetics ; 9 (2014), 8. - S. 1108-1119. - ISSN 1559-2294. - eISSN 1559-2308

Link to publication

https://dx.doi.org/10.4161/epi.29315

Institutions

UKU. Klinik für Innere Medizin III

Subject headings

[Free subject headings]: acute myeloid leukemia | DNA methylation | non-CGI region | DNMT3A | Homeobox gene family | ACUTE MYELOID-LEUKEMIA | GLOBAL DNA METHYLATION | IDH2 MUTATIONS | PATTERNS | METHYLTRANSFERASE | HYPERMETHYLATION | METHYLOME | PROGNOSIS | DEMETHYLATION | EXPRESSION
[DDC subject group]: DDC 610 / Medicine & health

Metadata

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