Softdrinks und ihre Auswirkungen auf die Prävalenz einer Steatosis hepatis
Auch gedruckt in der BibliothekW: W-H 13.148
Ressourcen- / MedientypDissertation, Text
Datum der Freischaltung2012-12-21
Objective: Objective of the present study was to elucidate the effects of soft drink consumption on the prevalence of hepatic steatosis in a randomly selected population-based collective. Materials/Methods: A total of 1,435 subjects (54.6 % women, 45.4 % men; average age 42.3 ± 12.8 years) underwent upper abdominal sonographic examination. Subjects were questioned regarding their soft drink consumption and their body-mass index (BMI), waist-to-hip ratio (WHR), laboratory parameters and anthropometric data were documented. Results: The prevalence of hepatic steatosis in the overall collective stood at 26.1 % (n = 374; women, 39.0 %, n = 146; men, 61.0 %, n = 228). Consumption of soft drinks was reported by 20.8 % of subjects (n = 298); hepatic steatosis was diagnosed in 23.2 % (n = 69). The prevalence stood at 26.8 % among non-consumers. Male sex, greater age, higher BMI and WHR, and disorders such as diabetes mellitus, metabolic syndrome and hypertension increased the risk of developing hepatic steatosis (p < 0.0001). A higher prevalence of hepatic steatosis could not be demonstrated for consumers of soft drinks (p = 0.3715). Conclusion: No significant associatioin between the consumption of soft drinks and an increased prevalence of hepatic steatosis could be demonstrated in the study collective. Elevated prevalence rates for hepatic steatosis appear to be predominantly age and collective-dependent.