Genetic variability of drug-metabolizing enzymes: the dual impact on psychiatric therapy and regulation of brain function

Erstveröffentlichung
2013
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Authors
Stingl, J. C.
Brockmoeller, J.
Viviani, R.
Institutions
UKU. Institut für Naturheilkunde und Klinische Pharmakologie
UKU. Klinik für Psychiatrie und Psychotherapie III
Published in
Molecular Psychiatry ; 18 (2013), 3. - S. 273-287. - ISSN 1359-4184. - eISSN 1476-5578
Link to publication
https://dx.doi.org/10.1038/mp.2012.42
Keywords
CYP2D6; CYP2C19; DME endogenous substrates; DME in brain; polymorphic DMEs; psychotropic drugs; pharmacogenetic dose adjustments; DEBRISOQUINE 4-HYDROXYLASE CYP2D6; CYTOCHROME-P450 2D6 GENOTYPE; STATE PLASMA-CONCENTRATIONS; INDUCED MOVEMENT-DISORDERS; MESSENGER-RNA EXPRESSION; SERUM CONCENTRATIONS; POOR METABOLIZERS; CYP2C19 GENOTYPE; NO ASSOCIATION; CYP2D6-ASTERISK-4 POLYMORPHISM
Dewey Decimal Group
DDC 570 / Life sciences
DDC 610 / Medicine & health
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