High-throughput screening identified inherited genetic variations in the EGFR pathway contributing to skin toxicity of EGFR inhibitors

Erstveröffentlichung
2015
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Wissenschaftlicher Artikel


Authors
Hasheminasab, Sayed-Mohammad
Tzvetkov, Mladen V.
Schumann, Christian
Ruediger, Stefan
Boeck, Stefan
et al.
Institutions
UKU. Klinik für Innere Medizin II
UKU. Klinik für Innere Medizin I
Published in
Pharmacogenomics ; 16 (2015), 14. - S. 1605-1619. - ISSN 1462-2416. - eISSN 1744-8042
Link to publication
https://dx.doi.org/10.2217/pgs.15.97
Funding information
Wilhelm Sander-Stiftung, Germany / DERMATOXGEN [Nr. 2008.017.2]
GRK 1034 / Die Bedeutung genetischer Polymorphismen in der Onkologie: Von den Grundlagen zur individualisierten Therapie / DFG / GRK / 374717
Keywords
cetuximab; cytokines; EGFR; EGFR inhibitors; erlotinib; high-throughput nucleotide sequencing; skin toxicity; targeted sequencing; CELL LUNG-CANCER; ADVANCED SOLID TUMORS; INTRON 1; PHASE-I; POLYMORPHISMS; ASSOCIATION; RASH; GEFITINIB; VISUALIZATION; CARCINOMA
Dewey Decimal Group
DDC 610 / Medicine & health
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