Changes in cortical slow wave activity in healthy aging
Leirer, Vera Maria
FacultiesFakultät für Ingenieurwissenschaften und Informatik
Enhanced slow wave activity has been found in stroke patients, schizophrenia, depression, Alzheimer´s disease and post-traumatic stress disorder, but the relationship between slow wave activity and healthy aging is as yet unclear. We investigated the relationship between age and the frequency at which focal generators of delta waves appear in the healthy cerebral cortex, as well as whether this measure is associated with cognitive performance. Resting MEG was assessed in 53 healthy individuals aged 18 - 53. Focal slow wave generator dipole density decreased with age, but there was no relationship between dipole density and cognitive performance. These results emphasize the necessity of controlling for age in studies of slow wave activity in psychopathology. The final publication is available at www.springerlink.com.
Original publicationBrain imaging and behavior 5 (2011), 3, S. 222 - 228
Subject HeadingsIntelligenzleistung [GND]