Regulatorische DNA-Sequenzen in der Promoterregion des Streptococcus agalactiae Hämolysin-Genclusters
Dissertation
Fakultäten
Medizinische FakultätZusammenfassung
The ß-hemolysin of Streptococcus agalactiae is encoded by the cyl-operon. While the CovS/CovR regulator supresses ß-hemolysis, it is unknown, if additional regulatory mechanisms exist. To analyze regulation of ß-hemolysis, a promoter region fragment of the cyl genes that can cause a prominent hyperhemolytic phenotype of S. agalactiae was further characterized. By targeted mutagenesis, we identified several short DNA sequences harboring putative repressor molecule binding sites.
Erstellung / Fertigstellung
2011
Schlagwörter
[GND]: Streptococcus agalactiae[MeSH]: Hemolysin proteins
[Freie Schlagwörter]: CovS/CovR | cyl-Gene | ß-Hämolysin
[DDC Sachgruppe]: DDC 610 / Medicine & health
Metadata
Zur LanganzeigeDOI & Zitiervorlage
Nutzen Sie bitte diesen Identifier für Zitate & Links: http://dx.doi.org/10.18725/OPARU-2374
Appel, Katharina (2012): Regulatorische DNA-Sequenzen in der Promoterregion des Streptococcus agalactiae Hämolysin-Genclusters. Open Access Repositorium der Universität Ulm und Technischen Hochschule Ulm. Dissertation. http://dx.doi.org/10.18725/OPARU-2374
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