Polymorphisms related to ORMDL3 are associated with asthma susceptibility, alterations in transcriptional regulation of ORMDL3, and changes in T(H)2 cytokine levels

Erstveröffentlichung
2015Authors
Schedel, Michaela
Michel, Sven
Gaertner, Vincent D.
Toncheva, Antoaneta A.
Depner, Martin
Wissenschaftlicher Artikel
Published in
Journal of Allergy and Clinical Immunology ; 136 (2015), 4. - S. 893+. - ISSN 0091-6749. - eISSN 1097-6825
Link to publication
https://dx.doi.org/10.1016/j.jaci.2015.03.014Faculties
Medizinische FakultätInstitutions
Institut für Epidemiologie und Medizinische BiometrieSubject headings
[Free subject headings]: Asthma | association study | polymorphism | ORMDL3 | chromosome 17q21 | promoter activity | T(H)2 cytokine | upstream stimulatory factor | transcriptional regulation | ENDOPLASMIC-RETICULUM STRESS | AIRWAY EPITHELIAL-CELLS | SIGNAL TRANSDUCER | IGE LEVELS | EXPRESSION | GENE | CHILDREN | activation | INTERLEUKIN-8 | POPULATION[DDC subject group]: DDC 610 / Medicine & health