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[18F]FLT-PET zur Evaluation der Proliferation und des Therapieansprechens maligner Lymphome

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vts_7699_11058.pdf (2.021Mb)
70 Seiten
Veröffentlichung
2011-07-15
Authors
Kratochwil, Durda
Dissertation


Faculties
Medizinische Fakultät
Abstract
In this study the uptake of positron emitting thymidine analogue 18F-Fluorothymidin (18F-FLT) was positively correlated with histologic determined proliferation index (Ki-67) in a patient study. In the second part, it was evaluated that anti-proliferative therapies translate into an early decline of 18F-FLT uptake in a mouse model. Therefore 18F-FLT is a promising tracer for early prediction of therapy response and warrants further investigation.
Date created
2010
Subject headings
[GND]: Malignes Lymphom | Positronen-Emissions-Tomographie
[MeSH]: Lymphoma
[Free subject headings]: [18F]FLT
[DDC subject group]: DDC 610 / Medicine & health
License
Standard (Fassung vom 01.10.2008)
https://oparu.uni-ulm.de/xmlui/license_v2

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DOI & citation

Please use this identifier to cite or link to this item: http://dx.doi.org/10.18725/OPARU-2227

Kratochwil, Durda (2011): [18F]FLT-PET zur Evaluation der Proliferation und des Therapieansprechens maligner Lymphome. Open Access Repositorium der Universität Ulm und Technischen Hochschule Ulm. Dissertation. http://dx.doi.org/10.18725/OPARU-2227
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